Propylene glycol is an organic compound (diol), usually slightly Sweet, odorless, colorless and transparent oily liquid, hygroscopic and easily mixed with water, acetone, and chloroform. Propylene glycol has a wide range of applications and is often used as a hygroscopic agent, antifreeze, lubricant and solvent in the food, pharmaceutical and cosmetic industries. Propylene glycol supply points out: Propylene glycol, which is widely used in various industries, is divided into two types: 1,2-propanediol and 1,3-propanediol. 1,2-Propylene glycol has good viscosity and hygroscopicity and is widely used in the food, pharmaceutical and cosmetic industries.
Propylene glycol has the following effects on drugs:
Propylene glycol has good solubility and can dissolve many drugs such as sulfonamides, local anesthetics, and vitamin A. , vitamin D, sex hormones, chloramphenicol and many volatile oils, which are miscible with water, glycerin, ethanol, and can also be dissolved in ether and chloroform, but they are also not miscible with fatty oils.
A mixture of propylene glycol and water in a certain proportion can delay the hydrolysis of certain drugs and increase their stability.
When its concentration is selected appropriately, it can be used as a solvent for injections and has quick-acting or prolonged-acting effects.
A certain concentration of propylene glycol can be used as a penetration enhancer for drug absorption through the skin or mucous membranes.
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