Anhydrous N,N-Dimethylformamide

CAS: 68-12-2Molecular formula: C3H7NOMolecular weight: 73.09Chinese name:

N,N-Dimethylformamide

Formyldimethylamide

N-Formyldimethylformamide Amine

Dimethylformamide

DMF

DMFA

Anhydrous N,N-Dimethylformamide

Dimethylformamide (DMF)

English name:

N,N-Dimethylformamide

Formyldimethylamine

N,N-dimethyl-Formamide

N-Formyldimethylamine

n,n-dimethyl-formamid

dimethyl formamide

dimethylamid kyseliny mravenci

dimethylamid kyseliny mravenci (czech)

dimethylformamid

dimethylformamid (german)

dimethylformamide

dimetilformamide

dimetilformamide (italian)

dimetylformamidu

dimetylformamidu (czech)

dmf (amide)

dwumetyloformamid

dwumetyloformamid (polish)

epa pesticide chemical code 366200

amide, n,n-dimethyl-formic acid

n,n-dimethyl formamide

n,n-dimethylmethanamide

n,n-dimetilformamida (spanish)

nci-c60913

nsc 5356

u-4224

Formamide,N,N-dimethyl -

dlmethylformamide

N,N-dimethyl-formamide

N,N-Dimethylformamide,Spectrophotometric Grade

N,N-Dimethylformamide,HPLC Grade

N,N-Dimethylformamide ,ACS

N,N-Dimethylformamide,anhydrous,amine free

N,N-Dimethylformamide,anhydrous

Description of properties: Colorless transparent liquid. It is a polar inert solvent. It can be freely mixed with water and most organic solvents except halogenated hydrocarbons. Melting point -61°C, boiling point 152.8°C, 76°C (5.2kPa), relative density 0.9445 (25/4°C), refractive index 1.4269. The flash point is 58°C, and the spontaneous ignition point is 445°C. It has good solubility and chemical stability for various organic and inorganic compounds. The vapor pressure at 25°C is 0.493kPa. Production method: Since the first synthesis of dimethylformamide by the reaction of formic acid and dimethylamine in 1899, the development The process of synthesizing dimethylformamide with different raw materials, such as dimethylamine-carbon monoxide method, formamide-dimethylamine method, hydrogen cyanide-methanol method, acetonitrile-methanol method, methyl formate-dimethylamine method , Chloral-dimethylamine method and so on. However, the industrial production abroad is still dominated by the dimethylamine-carbon monoxide method. 1. Methyl formate-dimethylamine method generates methyl formate by esterification of formic acid and methanol, then reacts with dimethylamine in the gas phase to generate dimethylformamide, and then recovers methanol and unreacted methyl formate after distillation to reduce The finished product is obtained by pressure distillation. 2. The dimethylamine-carbon monoxide method is obtained by the direct reaction of dimethylamine and carbon monoxide under the action of sodium methoxide. The reaction conditions are 1.5-2.5 MPa and 110-150°C. The crude product is obtained by distillation. 3. Methyl formate is obtained by oxo-synthesis of carbon monoxide and methanol at a temperature of 80-100°C under high pressure, and then reacted with dimethylamine to form dimethylformamide, and the finished product is obtained after rectification. 4. The chloral method is obtained by the reaction of chloral and dimethylamine. Uses: Dimethylformamide is not only a chemical raw material with a wide range of uses, but also a excellent solvent. Dimethylformamide is a good solvent for various high polymers such as polyethylene, polyvinyl chloride, polyacrylonitrile, polyamide, etc., and can be used for wet spinning of synthetic fibers such as polyacrylonitrile fibers and synthesis of polyurethane; It is used for making plastic films; it can also be used as a paint remover for removing paint; it can also dissolve some low-solubility pigments, making the pigments have the characteristics of dyes. Dimethylformamide is used for the extraction of aromatics and for the separation and recovery of butadiene from the C4 fraction and the separation and recovery of isoprene from the C5 fraction. It can also be used as an effective reagent for the separation of non-hydrocarbon components from paraffin . It has good selectivity for the solubility of isophthalic acid and terephthalic acid: the solubility of isophthalic acid in dimethylformamide is greater than that of terephthalic acid, and solvent extraction or partial Crystallization can separate the two. In the petrochemical industry, dimethylformamide can be used as a gas absorbent to separate and refine gases. In organic reactions, dimethylformamide is not only widely used as a reaction solvent, but also an important intermediate in organic synthesis. In the pesticide industry, it can be used to produce dimeform; in the pharmaceutical industry, it can be used to synthesize iodopyrimidine, doxycycline, cortisone, vitamin B6, iodine glycoside, repellent, pyrantel, N-formyl sarcoid, anti Oncosine, methoxy mustard, Bian nitrogen mustard, cyclohexyl nitrosourea, furofluorouracil, tranexamic acid, befenmethasone, megestrol, bilivitamin, chlorpheniramine and so on. Dimethylformamide has a catalytic effect in the reactions of hydrogenation, dehydrogenation, dehydration and dehydrohalogenation, which reduces the reaction temperature and improves the purity of the product.