Ethylbisiminomethylguaiacol manganese chloride (EUK-134) has super antioxidant properties and has good future application prospects.

Ethylbisiminomethylguaiacol manganese chloride, EUK-134, is a synthetic, highly purified component that mimics the activity of superoxide dismutase (SOD) and catalase (CAT) in the body. EUK-134 appears as a reddish-brown crystal powder with a slightly unique odor. It is slightly soluble in water, soluble in propylene glycol and other polyols, and decomposes when exposed to acid.

EUK-134 is a new product developed based on SOD. As a small molecule compound, EUK-134 can directly enter the skin to play a role, solving the problem of large SOD molecules and poor stability. As one of the raw materials of cosmetics, EUK-134 has dual activity, can scavenge superoxide free radicals, has the effects of brightening skin, improving oily skin, relieving skin inflammation, keeping skin translucent and white, and has regenerative ability and stability better than SOD and CAT. Based on its super antioxidant and regenerative capabilities, EUK-134 will be increasingly widely used in anti-aging cosmetics, sunscreen cosmetics, whitening cosmetics, skin repair products and other fields.

With the deepening of research, the number of preparation methods for EUK-134 has gradually increased, involving raw materials including ethylenediamine o-vanillin, ethylbisiminomethylguaiacol manganese acetate, disalikenal ethylenediamine, etc. Since the preparation process involves multiple chemical reactions and purification steps, EUK-134 is difficult to produce and the market price is high, usually around 250,000/kg. Due to this limitation, EUK-134 is mainly used in mid-to-high-end cosmetic products, such as Estee Lauder, La Mer, etc.

According to the “2023-2027 Ethylbisiminomethylguaiacol manganese chloride (EUK-134) industry market supply and demand status and “In-depth investigation and analysis report on industry operating indicators” shows that my country’s EUK-134 related R&D or suppliers include Shanghai University of Traditional Chinese Medicine, Baiyun Meiwan International Cosmetic Research Institute, Huzhou Purui Biomedicine, and Yunxi Chemical Industry , Hubei Shixing Chemical Industry, Wuhan Xinweiye Chemical Industry, etc. Thanks to advances in preparation technology, the purity of EUK-134 products has been greatly improved, and the purity of some products has reached more than 99%.

my country’s cosmetics market is huge. Under the beauty economy, consumers are paying more and more attention to their skin, and the cosmetics market still has broad room for growth. In 2022, the size of my country’s cosmetics market will be around 418 billion yuan, and it is expected that this market size will reach more than 700 billion yuan in 2027. As one of the raw materials of cosmetics, EUK-134 has super antioxidant properties. As the scale of the cosmetics market expands, the application demand for EUK-134 will be further released, and the industry has broad prospects for development.

Industry analysts said that at present, the EUK-134 market is still in the early stages of development, and EUK-134 has not yet been realized due to its high price. Widely used and only found in a few cosmetic products. However, as a highly efficient antioxidant, EUK-134 has broad application prospects and market development potential under the background of beauty economy. In the future, as the preparation process is optimized and production costs decrease, EUK-134 is expected to be widely used in medicine, chemical industry, agriculture and other fields in addition to cosmetics.