Sales of ketoconazole ointment in my country will exceed 200 million in 2022, and the market demand for ketoconazole is strong

Ketoconazole is an imidazole compound that appears as a white to off-white crystalline powder under normal conditions. Ketoconazole is a broad-spectrum antifungal drug that blocks the biosynthesis of active components of fungal cell membranes, further affects the permeability of fungal cell membranes, and ultimately inhibits fungal growth. Ketoconazole products are effective against all diseases caused by fungal infections inside and outside the human body, such as tinea corporis, tinea cruris, tinea manuum and pedis caused by various ringworms, candida infection of the skin, candidal vulvovaginitis, and mottling caused by Malassezia. Pityriasis, seborrheic dermatitis, etc., all have good curative effects.

At present, ketoconazole is mainly produced industrially through chemical synthesis. The main raw materials of the chemical synthesis method are 1-acetyl 4-4 (4-hydroxyphenyl) piperazine, sodium cyanide, dimethyl sulfate, etc. There are many production steps and high operating requirements. In recent years, microbial fermentation has attracted attention from the ketoconazole industry. Microbial fermentation mainly uses microbial metabolites as raw materials to produce and process pure ketoconazole. This method has the advantages of simple process, low cost, high product quality, and good production efficiency. , it is expected that with the promotion of technology in the future, microbial fermentation will become the mainstream production process in the ketoconazole industry.

According to the “2023-2028 China Ketoconazole Industry Market In-depth Research and Development Prospects Forecast Report released by the Industrial Research Center, According to different properties and uses, ketoconazole products can be divided into ketoconazole cream, ketoconazole lotion, ketoconazole suppository, ketoconazole spray, ketoconazole tablets, ketoconazole capsules, etc., among which ketoconazole Conazole ointment is the main product. Ketoconazole ointment is mainly used to treat various types of skin tinea diseases caused by fungal infections. There is a high incidence of skin ringworm in my country, with a prevalence rate as high as 4.5%. In 2022, sales of ketoconazole ointment in physical pharmacies in Chinese cities will reach more than 200 million. The market demand for ketoconazole products represented by ketoconazole ointment is huge.

Ketoconazole lotion is a topical drug that has good curative effect on scalp pityriasis, localized pityriasis versicolor, and seborrheic dermatitis. As the pace of life accelerates and residents pay more attention to their own health, shampoo products containing ketoconazole are favored by the market, driving the market demand for ketoconazole.

At present, there are many ketoconazole companies in my country, mainly small and medium-sized chemical companies, such as Hubei Yikanyuan Chemical, Xi’an Kangnuo Chemical, Zhengzhou Givaudan Chemical, etc. There are also some pharmaceutical companies with ketoconazole production capacity to achieve self-sufficiency. At the same time, it also sells to external parties, such as Ruichengkang Pharmaceutical Technology, Henan Qiande Pharmaceutical, Jiangsu Rongshuo Pharmaceutical, etc. Industry analysts said that my country’s ketoconazole companies should strengthen technological innovation, innovate production processes, and put microbial fermentation methods into production practice as soon as possible , improve product quality and production efficiency. At the same time, ketoconazole products have a high degree of homogeneity. Ketoconazole companies should also work hard to broaden ketoconazole application channels and expand the demand market.