The market demand for 2-amino-5-chloro-N,3-dimethylbenzamide (K amine) continues to grow and my country’s supply capacity will increase

2-Amino-5-chloro-N,3-dimethylbenzamide, referred to as K amine, is an organic substance that appears as white or off-white crystalline powder, slightly soluble in water, and soluble in methanol and ethanol. As an intermediate, K-amine is widely used in the fields of medicine and pesticides. In the field of pesticides, K-amine is one of the key intermediates of chlorantraniliprole.

There are many processes reported in K amine literature, including the process using 2-amino-N,3-dimethylbenzamide as raw material, the process using 2-amino-5-chloro-3-methylbenzoic acid as raw material, and the process using 2-amino-N,3-dimethylbenzamide as raw material. The process using 2-nitro-3-methylbenzoic acid as raw material, the process using 7-methylisatin as raw material, etc. Among them, the process using 2-nitro-3-methylbenzoic acid as raw material is the most common.

K-amine is the key intermediate of chlorantraniliprole. Chlorantraniliprole is a new o-carbamidobenzamide insecticide, launched by DuPont in the United States. The patent compound of chlorantraniliprole expires on August 13, 2023. Benefiting from this, domestic companies have begun to invest in building new production capacity and register new products. Since 2020, the total declared production capacity of domestic chlorantraniliprole has been Reaching about 100,000 tons.

According to the “China 2-amino-5-chloro-N,3-dimethylbenzamide (K amine) industry from 2023 to 2027 released by the Industrial Research Center Market supply and demand status and development trend forecast report” shows that my country’s K-amine related suppliers include Jiangsu Youpu Biochemical Technology Co., Ltd., Jiujiang Shanshui Technology Co., Ltd., Jiangxi Zhongli Chemical Co., Ltd., Jiangsu Qizhou Green Chemical Co., Ltd., etc. The global chlorantraniliprole market is developing strongly, and the market demand for K-amine is strong. In 2022, India’s K-amine import volume will reach 200 tons.

Global sales of chlorantraniliprole in 2022 will be approximately US$2.45 billion, with market participants including FMC, India’s Best Agrolife Limited, GSP Crop Science, Germany’s Bayer Group, etc. At present, the chlorantraniliprole market has ushered in a period of explosive growth, and the application demand for upstream raw materials such as K-amine and K-acid will be further released.

There are many chlorantraniliprole-related projects under construction or planned in my country. In order to meet the demand for raw materials and create advantages in the entire industry chain, chlorantraniliprole-related devices are often equipped with upstream main raw materials. For example, the Shandong Youdao Chemical project can produce 1,000 tons/year of chlorantraniliprole and 2,000 tons/year of 2-amino-5-chloro-N,3-dimethylbenzamide; the projects of Liaoning Fengshou Pesticide Co., Ltd. include 3-Chloro-2-hydrazinopyridine, 3-bromo-1-(3-chloropyridin-2-yl)-1H-pyridine-5-carboxylic acid, 2-amino-5chloro-N,3-dimethyl Benzamide, 2-amino-5-chloro-3-methylbenzoic acid and four chlorantraniliprole intermediates.

Industry analysts said that K amine is a key intermediate for chlorantraniliprole. With the expansion of chlorantraniliprole production capacity , the market demand for K amine has increased significantly, and the industry has broad prospects for development. Under the background of increasingly strict environmental protection supervision, the green and environmentally friendly development of chlorantraniliprole will be an inevitable trend. In order to comply with industry trends, K amine production will also transform into a green and environmentally friendly direction.