Crotonic acid (crotonic acid) has a large market space and good application prospects in the medical field.

Crotonic acid, also known as crotonic acid, has a chemical formula of C4H6O2 and is an organic compound. Crotonic acid appears as a white to light yellow crystalline powder, contains an odor similar to butyric acid, and is soluble in most organic solvents such as water, toluene, ether, and acetone. Crotonic acid is an unsaturated fatty acid with strong reactivity and is widely used in medicine, fungicides, plasticizers, synthetic resins, feed processing, coatings and other fields.

Crotonaldehyde oxidation method is the main preparation method of crotonic acid. According to the different oxidants used, it can be divided into two types: peroxide oxidation method and oxygen oxidation method. Oxygen oxidation methods include acid catalytic oxidation methods and metal oxide catalytic oxidation methods. The metal oxide catalytic oxidation method refers to using aluminum trioxide (Al2O3) as the raw material to prepare a catalyst, adding crotonaldehyde and acetone, and then introducing oxygen to obtain the finished product after a full reaction. This method has high yield of finished product and high utilization rate of raw materials. It has high advantages and is widely used in the production process of crotonic acid.

Crotonic acid is used in a wide range of applications, including medicine, fungicides, plasticizers, synthetic resins, feed processing, and coatings. In the medical field, crotonic acid can be used as a pharmaceutical intermediate to produce anti-cancer and antibacterial drugs; in the field of feed processing, crotonic acid can be used as a feed additive to promote the growth and development of animals; in the field of coatings, crotonic acid is polyacetic acid The main raw material for vinyl coatings. Driven by application demand, the market space of crotonic acid continues to expand. According to the “2023-2028 China Crotonic Acid (Butenoic Acid) Industry Market In-depth Research and Development Prospects Forecast Report》shows that the global crotonic acid market will reach nearly US$100 million in 2022.

In recent years, my country’s scientific research institutions have continued to increase research on the application of crotonic acid in the medical field and have made many new progresses. At the end of 2019, Nankai University’s Lin Liu research team used a mixture of crotonic acid and rock inhibitors to successfully convert mouse granulosa cells into oocytes and cultivate healthy offspring with fertility. This technology is expected to be used in the future in the future It has been applied in the fields of fertility treatment and assisted reproductive medicine.

At present, my country’s crotonic acid market is dominated by small and medium-sized enterprises, and the industry concentration is low. Major players in my country’s crotonic acid market include Wuhan Jiyesheng Chemical Co., Ltd., Wuhan Rongcan Biotechnology Co., Ltd., Nantong Huixin Chemical Co., Ltd., Zhengzhou Tuozhixiang Chemical Co., Ltd., Hunan Jinneng Technology Co., Ltd., etc.

          Industry analysts said that crotonic acid is extremely reactive and widely used in many fields. In the future, as research continues to deepen, the application scope of crotonic acid will be further expanded. There are many crotonic acid manufacturers in my country, but the market is dominated by small and medium-sized enterprises. It is expected that companies with high-quality crotonic acid production capabilities will occupy more market shares in my country in the future.