Epoxy curing agent Knowledge Inosine Inosine

Inosine Inosine

广告位

Inosine structural formula

Structural formula

Business number 019P
Molecular formula C10H12N4O5
Molecular weight 268.23
label

9-β-D-Ribofuranosylhypoxanthine,

Inosine;,

Hypoxanthine 9-β-D-ribofuranoside,

Treat liver disease

Numbering system

CAS number:58-63-9

MDL number:MFCD00066770

EINECS number:200-390-4

RTECS number:NW7460000

BRN number:624889

PubChem number:24896051

Physical property data

1. Properties: White needle-like crystals. Odorless. Slightly bitter taste.

2. Density (g/mL, 25/4℃): Undetermined.

3. Relative vapor density (g/mL, air=1): Undetermined

4. Melting point (ºC): 218℃ (decomposition)

5. Boiling point (ºC, normal pressure): Undetermined

6. Boiling point (ºC, 5.2kPa): Undetermined

7. Refractive index: Undetermined

8. Flash point (ºC): Undetermined

9. Specific rotation (º): [α]D18-49.2° (C=0.9, in water), [α]D22-52.6° (C=2.5, water)

10. Autoignition point or ignition temperature (ºC): Undetermined

11. Vapor pressure (kPa, 25ºC): Undetermined

12. Saturated vapor pressure (kPa, 60ºC): Undetermined

13. Heat of combustion (KJ/mol): Undetermined

14. Critical temperature (ºC) : Undetermined

15. Critical pressure (KPa): Undetermined

16. Log value of oil-water (octanol/water) partition coefficient: Undetermined

17. Explosion upper limit (%, V/V): Undetermined

18. Explosion lower limit (%, V/V): Undetermined

19. Solubility: 20℃ 100ml of water dissolves 1.6g of product. Slightly soluble in dilute hydrochloric acid and alkali hydroxide solutions, very slightly soluble in ethanol. It is easily hydrolyzed in dilute inorganic acids to produce hypoxanthine and D-ribose.

Toxicological data

1. Acute toxicity: rat oral LD50: >10000mg/kg; rat intraperitoneal LD50: 2900mg/kg; rat intravenous LD50: >2mg/kg; mouse oral LC50: >20mg/kg; mouse intraperitoneal LC50: 3175mg/kg; mouse subcutaneous LC50: 5mg/kg; mouse intravenous LC50: >2800mg/kg2. Other multiple dose toxicity: rat oral TDLo: 558mg/kg/93D-C

3. Mutagenicity Sex: DNA damageTEST system: mammal – species not lymphocytes: 60mmol/L

Ecological data

None

Molecular structure data

1. Molar refractive index: 58.89

2. Molar volume (cm3/mol): 128.6

3. Isotonic specific volume (90.2K): 411.3

4. Surface tension (dyne/cm): 104.4

5. Polarizability (10-24cm3): 23.34

Compute chemical data

1. Reference value for hydrophobic parameter calculation (XlogP): None

2. Number of hydrogen bond donors: 4

3. Number of hydrogen bond acceptors: 6

4. Number of rotatable chemical bonds: 2

5. Number of tautomers: 3

6. Topological molecule polar surface area 129

7. Number of heavy atoms: 19

8. Surface charge: 0

9. Complexity: 405

10. Number of isotope atoms: 0

11. Determine the number of atomic stereocenters: 4

12. Uncertain number of atomic stereocenters: 0

13. Determine the number of chemical bond stereocenters: 0

14. Number of uncertain chemical bond stereocenters: 0

15. Number of covalent bond units: 1

Properties and stability

None

Storage method

This product should be sealed and stored in a cool, dry place.

Synthesis method

(1) Corynebacterium fermentation produces inosinic acid, and then chemically removes the phosphoric acid to obtain inosine.

(2) Mutated Bacillus with double auxotrophs for adenine and thiamine strain, one-step fermentation to prepare inosine.

Purpose

1. Biochemical research. It is used medicinally to promote white blood cell proliferation.

2.It is used for leukopenia or thrombocytopenia, liver disease and heart disease.

广告位
This article is from the Internet, does not represent the position of Epoxy curing agent, reproduced please specify the source.https://www.dmp-30.vip/archives/81135

author:

Previous article
Next article
Contact Us

Contact us

+86 - 152 2121 6908

Online consultation: QQ交谈

E-mail: info@newtopchem.com

Working hours: Monday to Friday, 9:00-17:30, closed on holidays
Follow wechat
Scan wechat and follow us

Scan wechat and follow us

Follow Weibo
Back to top
Home
Phone
Products
Search