Epoxy curing agent Knowledge 5,7-Diiodo-8-hydroxyquinoline 5,7-Diiodo-8-hydroxyquinoline

5,7-Diiodo-8-hydroxyquinoline 5,7-Diiodo-8-hydroxyquinoline

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5,7-diiodo-8-hydroxyquinoline structural formula

Structural formula

Business number 01U9
Molecular formula C9H5I2NO
Molecular weight 396.95
label

5,7-diiodo-8-hydroxyquinoline,

Dihydroxyquine,

Diiodoquine,

5,7-Diiodoquinolin-8-ol,

5,7-Diiodo-8-quinolinol

Numbering system

CAS number:83-73-8

MDL number:MFCD00006789

EINECS number:201-497-9

RTECS number:VC5775000

BRN number:None

PubChem number:24893382

Physical property data

1. Characteristics: light yellow to yellow-brown fine crystalline powder.


2. Density (g/mL ,25/4):Undetermined


3. Relative vapor density (g /mL,AIR= 1): Undetermined


4. Melting point (ºC): about214(decomposition)


5. Boiling point (ºC,Normal pressure): Undetermined


6. Boiling point (ºC,5.2 kPa): Undetermined


7. Refractive Index: Undetermined


8. Flash point (ºC): Undetermined


9. Specific optical rotation (º ): Undetermined


10. Autoignition point or ignition temperature (ºC): Undetermined


11. Vapor pressure (kPa, 25ºC): Undetermined


Cat caliberLDLO:300mg/kg;


Pig caliberLDLO:50mg/kg;


2. Teratogenicity


E. coli: 260nmol/plate;


Mouse: 80 mg/kg;

Ecological data

None yet

Molecular structure data

1. Molar refractive index: 69.88


2. Molar volume (m3/mol):159.3


3. isotonic specific volume (90.2K):471.4


4. Surface Tension (dyne/cm):76.6


5. Polarizability10-24cm3):27.70

Compute chemical data

1. Reference value for hydrophobic parameter calculation (XlogP): 3.1

2. Number of hydrogen bond donors: 1

3. Number of hydrogen bond acceptors: 2

4. Number of rotatable chemical bonds: 0

5. Number of tautomers: 2

6. Topological molecule polar surface area 33.1

7. Number of heavy atoms: 13

8. Surface charge: 0

9. Complexity: 191

10. Number of isotope atoms: 0

11. Determine the number of atomic stereocenters: 0

12. Uncertain number of atomic stereocenters: 0

13. Determine the number of chemical bond stereocenters: 0

14. Number of uncertain chemical bond stereocenters: 0

15. Number of covalent bond units: 1

Properties and stability

None yet

Storage method

This product should be sealed in Store in a cool and dry place.

Synthesis method

By8-Hydroxyquinoline is obtained by iodination.

Purpose

Used as anti-amidamide Pakistani medicine, antiseptics, metal chelating agents, cation analysis reagents. Diiodoquinoline, quiniodoform, and clioiodoquinoline are all halogenated8-Hydroxyquinoline intestinal anti-amoebic drugs are effective against amoebic dysentery and have no effect on extraintestinal amebic protozoa. In recent years, it has been reported abroad that this type of drug can cause subacute myelooptic neuropathy, so it has been banned in Japan and the United States. However, this disease is less common with iodoquinoline than with clioquinoline.

fareast-font-family: Arial”>4. Surface Tension (dyne/cm):76.6


5. Polarizability10-24cm3):27.70

Compute chemical data

1. Reference value for hydrophobic parameter calculation (XlogP): 3.1

2. Number of hydrogen bond donors: 1

3. Number of hydrogen bond acceptors: 2

4. Number of rotatable chemical bonds: 0

5. Number of tautomers: 2

6. Topological molecule polar surface area 33.1

7. Number of heavy atoms: 13

8. Surface charge: 0

9. Complexity: 191

10. Number of isotope atoms: 0

11. Determine the number of atomic stereocenters: 0

12. Uncertain number of atomic stereocenters: 0

13. Determine the number of chemical bond stereocenters: 0

14. Number of uncertain chemical bond stereocenters: 0

15. Number of covalent bond units: 1

Properties and stability

None yet

Storage method

This product should be sealed in Store in a cool and dry place.

Synthesis method

By8-Hydroxyquinoline is obtained by iodination.

Purpose

Used as anti-amidamide Pakistani medicine, antiseptics, metal chelating agents, cation analysis reagents. Diiodoquinoline, quiniodoform, and clioiodoquinoline are all halogenated8-Hydroxyquinoline intestinal anti-amoebic drugs are effective against amoebic dysentery and have no effect on extraintestinal amebic protozoa. In recent years, it has been reported abroad that this type of drug can cause subacute myelooptic neuropathy, so it has been banned in Japan and the United States. However, this disease is less common with iodoquinoline than with clioquinoline.

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