Epoxy curing agent Knowledge Choline chloride Choline chloride

Choline chloride Choline chloride

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Choline chloride structural formula

Structural formula

Business number 01EQ
Molecular formula C5H14ClNO
Molecular weight 139
label

Kourida, sweet potato enlarging factor,

Plant Growth Regulator

Numbering system

CAS number:67-48-1

MDL number:MFCD00011721

EINECS number:200-655-4

RTECS number:KH2975000

BRN number:3563126

PubChem number:24892968

Physical property data

1. Properties: White hygroscopic crystals, odorless, fishy smell, easy to deliquesce, unstable in alkali solution

2. Density (g/mL, 25/4℃): Uncertain

3. Relative vapor density (g/mL, air=1): Uncertain

4. Melting point (ºC): 302-305 (dec.)(lit.)

5. Boiling point (ºC, normal pressure): Uncertain

6. Boiling point (ºC, 5.2kPa): Uncertain

7. Refractive index: Uncertain Confirm

8. Flash point (ºC): Uncertain

9. Specific rotation (º): Uncertain

10. Autoignition point or ignition Temperature (ºC): Uncertain

11. Vapor pressure (kPa, 25ºC): Uncertain

12. Saturated vapor pressure (kPa, 60ºC): Uncertain

13. Heat of combustion (KJ/mol): Uncertain

14. Critical temperature (ºC): Uncertain

15. Critical pressure (KPa): Uncertain

16. Log value of oil-water (octanol/water) partition coefficient: Uncertain

17. Explosion upper limit (%, V/V): Uncertain

18. Lower explosion limit (%, V/V): Uncertain

19. Solubility: Easily soluble in water and ethanol, insoluble in ether, petroleum ether, benzene and carbon disulfide

Toxicological data

None yet

Ecological data

None yet

Molecular structure data

None yet

Compute chemical data

1. Reference value for hydrophobic parameter calculation (XlogP): None

2. Number of hydrogen bond donors: 1

3. Number of hydrogen bond acceptors: 2

4. Number of rotatable chemical bonds: 2

5. Number of tautomers: none

6. Topological molecule polar surface area 20.2

7. Number of heavy atoms: 8

8. Surface charge: 0

9. Complexity: 46.5

10. Number of isotope atoms: 0

11. Determine the number of atomic stereocenters: 0

12. Uncertain number of atomic stereocenters: 0

13. Determine the number of chemical bond stereocenters: 0

14. Number of uncertain chemical bond stereocenters: 0

15. Number of covalent bond units: 2

Properties and stability

White crystal. Slightly fishy�. Salty and bitter taste, easy to deliquesce and unstable in alkaline solution.

Storage method

This product should be sealed and stored in a cool, dry place away from light.

Synthesis method

1) Trimethylamine hydrochloride and a certain amount of ethylene oxide are continuously prepared into the choline chloride solution by a pump and fed into the reactor continuously. The residence time of the reactants in the reactor is 1-1.5h. . The reaction is carried out under stirring, and the products are continuously drawn out to keep the liquid level in the reactor stable. The crude choline chloride product drawn from the reactor enters the stripping tower, and 60-80% choline chloride liquid product is obtained from the bottom of the tower. (2) React trimethylamine hydrochloride with ethylene oxide, then add organic acid to neutralize and concentrate to prepare choline chloride. (3) Choline chloride is produced by reacting chloroethanol with trimethylamine.

A product obtained from the reaction of trimethylamine and ethylene oxide. The product can also be obtained by reacting chloroethanol with trimethylamine under the catalysis of a small amount of ethylene oxide or alkaline substances.

Purpose

1. As a feed additive, choline chloride has the following physiological effects: it can prevent fat accumulation and tissue degeneration in the liver and kidneys; it can promote the recombination of amino acids; it can increase the concentration of amino acids, especially the essential amino acid methionine. In vivo utilization. In Japan, 98% of choline chloride is used as an additive for animal feed such as chickens, pigs, beef cattle, fish and shrimps. Most of them are processed into powders. The preparation method of 50% powder is to add excipients of appropriate particle size in the mixer in advance, then dropwise add choline chloride aqueous solution, mix and dry. Some commercial powders also contain vitamins, minerals, drugs, etc. Choline chloride is a vitamin B drug, used for hepatitis, liver function degeneration, early cirrhosis, pernicious anemia and other diseases.
2.Choline is an important substance needed by livestock, poultry, and fish. In animals, it can regulate the metabolism and transformation of fat, effectively prevent and treat fat deposition and tissue degeneration in livestock and poultry organs, enhance the physical fitness and disease resistance of livestock and poultry, promote growth and development, and improve the utilization of amino acids. When there is a lack of choline in the feed of minks, pigs, rabbits, cattle and other livestock, the livestock will be stunted, with rough fur and soft bones, reduced growth, and frailty.

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