Tetrahydrofolate

Structural formula

Business number	03Q1
Molecular formula	C19H23N7O6
Molecular weight	445.4
label	5,6,7,8-Tetrahydropteroyl-L-glutamic acid, aromatic compounds

• Numbering system
• Physical property data
• Toxicological data
• Ecological data
• Molecular structure data
• Computing chemical data
• More
  • Properties and Stability
  • Storage method
  • Synthesis method
  • Purpose

Numbering system

CAS number:135-16-0

MDL number:MFCD00135583

EINECS number:205-181-1

RTECS number:MA0600800

BRN number:9238187

PubChem number:24900106

Physical property data

None

Toxicological data

Other multi-dose Data:

Rat subcutaneous TDLo: 18 gm/kg/5W-I

Reproduction data:

Big female rat Subcutaneous TDLo for 8-14 days after pregnancy: 70mg/kg

Little female mouse After pregnancy 7-13 days subcutaneously TDLo: 70mg/kg

Ecological data

None

Molecular structure data

Sub-property data:

1, Molar refractive index：107.81

2, Molar volume（m³/mol): 261.3

3, Isotonic specific volume（90.2K）：783.3

4, Surface tension（3.0 dyne/cm SPAN>): 80.6

5, Polarizability（ 0.5 10^-24cm³): 42.74

Compute chemical data

1. Reference value for hydrophobic parameter calculation (XlogP):-0.6

2. Number of hydrogen bond donors: 8

3. Number of hydrogen bond acceptors: 11

4. Number of rotatable chemical bonds: 9

5. Number of tautomers: 27

6. Topological molecular polar surface area (TPSA):207

7. Number of heavy atoms: 32

8. Surface charge: 0

9. Complexity: 834

10. Number of isotope atoms: 0

11. Determine the number of atomic stereocenters: 1

12. The number of uncertain atomic stereocenters: 1

13. Determine the number of stereocenters of chemical bonds: 0

14. Uncertain number of chemical bond stereocenters: 0

15. Number of covalent bond units: 1

Properties and stability

crystallize. Hygroscopic. sensitive to light

Storage method

Seal with argon gas and store in a dry place below 0℃ and away from light.

Synthesis method

None

Purpose

Biochemical research.

so-bidi-font-family: Arial”>Determine the number of stereocenters of chemical bonds: 0

14. Uncertain number of chemical bond stereocenters: 0

15. Number of covalent bond units: 1

Properties and stability

crystallize. Hygroscopic. sensitive to light

Storage method

Seal with argon gas and store in a dry place below 0℃ and away from light.

Synthesis method

None

Purpose

Biochemical research.