Vinblastine sulfate

Structural formula

Business number	03W8
Molecular formula	C46H60N4O13S
Molecular weight	909.05
label	Vincaleukoblastine sulfate salt

• Numbering system
• Physical property data
• Toxicological data
• Ecological data
• Molecular structure data
• Computing chemical data
• More
  • Properties and Stability
  • Storage method
  • Synthesis method
  • Purpose

Numbering system

CAS number:143-67-9

MDL number:MFCD00082457

EINECS number:205-606-0

RTECS number:YY8400000

BRN number:3659812

PubChem number:24278771

Physical property data

1. Physical property data:

1. Melting point (ºC): 267ºC

2. Specific optical rotation (º): -21.7 º

Toxicological data

2. �Physics data:

1, acute toxicity: rat oral LD50: 305 mg/kg;

Rat abdominal cavity LD50: 1 mg/kg;

Rat subcutaneous LD50: 355 mg/kg;

Rat veinLD50：37 mg/kg;

Mice orallyLD50: 423 mg/kg;

Mouse abdominal cavity LD50: 2700 ug/kg；

Mouse subcutaneous LD50: 324 mg/kg.

Ecological data

3. Ecological data:

Other harmful Effect: This substance may be harmful to the environment, and special attention should be paid to water bodies.

Molecular structure data

None

Compute chemical data

4. Calculated chemical data:

1. Hydrogen Bonding Number of donors: 5

2. Hydrogen Bonding Number of receptors: 16

3. Rotatable Number of chemical bonds: 10

4. Topological molecules Polar surface area (TPSA）：229

5. Heavy atoms Quantity: 64

6. Surface charge ：0

7. Complexity ：1780

8. Isotope atomic number:0

9. Determine the number of atomic stereocenters:9

10. Uncertain number of atomic stereocenters:0

11. Determine the number of stereocenters of chemical bonds:0

12. Uncertain number of chemical bond stereocenters:0

13. Number of covalent bond units: 2

Properties and stability

Stable under normal temperature and pressure.

Storage method

Save at 2-8ºC.

Synthesis method

None

Purpose

1.Anti-tumor drugs, used to treat Hodgkin’s disease and chorioepithelial carcinoma, and also have certain effects on lymphosarcoma, acute leukemia, breast cancer, etc..

2.Anti-tumor drug for malignant lymphoma

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1.Anti-tumor drugs, used to treat Hodgkin’s disease and chorioepithelial carcinoma, and also have certain effects on lymphosarcoma, acute leukemia, breast cancer, etc..

2.Anti-tumor drug for malignant lymphoma