sulfaacetyl

Structural formula

Business number	03WL
Molecular formula	C8H10N2O3S
Molecular weight	214.24
label	N-(4-aminobenzenesulfonyl)acetamide, acesulfonamide sodium salt, acesulfonamide, N-(4-Aminobenzenesulfonyl)acetamide

• Numbering system
• Physical property data
• Toxicological data
• Ecological data
• Molecular structure data
• Computing chemical data
• More
  • Properties and Stability
  • Storage method
  • Synthesis method
  • Purpose

Numbering system

CAS number:144-80-9

MDL number:MFCD00066501

EINECS number:205-640-6

RTECS number:AC8450000

BRN number:981718

PubChem number:24899803

Physical property data

1. Physical property data:

1. Character:White crystalline powder
-bidi-font-family: Tahoma”>2. Melting point (ºC): 182-184ºC
3. Solubility:Soluble in ethanol, slightly soluble in water or ether, almost insoluble in chloroform or benzene, soluble in dilute mineral acid or alkali hydroxide Solution.

Toxicological data

2. Toxicological data:

1, acute toxicity: rat intravenous LD50: 6600 mg/kg;

Mouse oral LD50: 16500 mg/kg;

Mouse abdominal cavity LD50: 606 mg/kg.

2. Reproductive toxicity: RatTDLo: 10 gm/kg

Ecological data

3. Ecological data:

Other harmful Effect: This substance may be harmful to the environment, and special attention should be paid to water bodies.

Molecular structure data

5. Molecular property data:

1. Molar refractive index:52.21

2. Molar volume (m³/mol):155.9

3. Isotonic specific volume (90.2K):424.7

4. Surface tension (dyne/cm):55.0

5. Polarizability(10^-24cm³）：20.69

Compute chemical data

1. Reference value for hydrophobic parameter calculation (XlogP): None

2. Number of hydrogen bond donors: 2

3. Number of hydrogen bond acceptors: 4

4. Number of rotatable chemical bonds: 2

5. Number of tautomers: 2

6. Topological molecule polar surface area 97.6

7. Number of heavy atoms: 14

8. Surface charge: 0

9. Complexity: 299

10. Number of isotope atoms: 0

11. Determine the number of atomic stereocenters: 0

12. Uncertain number of atomic stereocenters: 0

13. Determine the number of chemical bond stereocenters: 0

14. Number of uncertain chemical bond stereocenters: 0

15. Number of covalent bond units: 1

Properties and stability

Stable under normal temperature and pressure. 2. Moore Volume (m³/mol ): 155.9

3. Isotonic specific volume (90.2K):424.7

4. Surface tension (dyne/cm):55.0

5. Polarizability(10^-24cm³）：20.69

Compute chemical data

1. Reference value for hydrophobic parameter calculation (XlogP): None

2. Number of hydrogen bond donors: 2

3. Number of hydrogen bond acceptors: 4

4. Number of rotatable chemical bonds: 2

5. Number of tautomers: 2

6. Topological molecule polar surface area 97.6

7. Number of heavy atoms: 14

8. Surface charge: 0

9. Complexity: 299

10. Number of isotope atoms: 0

11. Determine the number of atomic stereocenters: 0

12. Uncertain number of atomic stereocenters: 0

13. Determine the number of chemical bond stereocenters: 0

14. Number of uncertain chemical bond stereocenters: 0

15. Number of covalent bond units: 1

Properties and stability

Stable under normal temperature and pressure.

Storage method

Save at 0-6ºC.

Synthesis method

Obtained by acidification of sodium sulfonamide acetate. Dissolve sodium sulfonamide acetate in water and use 5%Hydrochloric acid is adjusted to pH3.8-4 to precipitate sulfonamide acetyl. Filter, wash and dry to get the finished product.

Purpose

Medicine, used to treat conjunctivitis, trachoma and other eye infections.

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Storage method

Save at 0-6ºC.

Synthesis method

Obtained by acidification of sodium sulfonamide acetate. Dissolve sodium sulfonamide acetate in water and use 5%Hydrochloric acid is adjusted to pH3.8-4 to precipitate sulfonamide acetyl. Filter, wash and dry to get the finished product.

Purpose

Medicine, used to treat conjunctivitis, trachoma and other eye infections.