Organotin

Organotin The organotin compound is a metal organic compound formed by direct bonding of tin and carbon. Formula RnSnX4-n (n=1-4, R is an alkyl group or an aromatic group). There are two types of alkyl tin compounds and aromatic compounds. Its basic structure has a substituent, a disubstituted, a trisubstituted, and a tetrasubstituted (referring to the number of R). 10-20% of the tin production is used to synthesize organotin compounds. Chinese name: organotin Type: Organic Compound Uses: as a catalyst, stabilizer Hazard: the central nervous system can cause white matter edema General: RnSnX4-n use Main uses include: as a catalyst, stabilizer (such as dimethyl tin, dioctyltin, tetraphenyltin), agricultural pesticides, fungicides (such as dibutyltin, tributyltin, triphenyltin) and daily necessities Coatings and mold inhibitors. In the natural environment, these compounds react rapidly with heat, light, water, oxygen, ozone, and the like. After entering the organism, the small intestine or skin is easily absorbed, especially the trisubstituted body is most easily absorbed and distributed in the liver, kidney and brain. The liver-based microsomal drug metabolizing enzyme system dealkylates and dearomatizes rapidly. The trisubstituted body has a biological half-life of 3 to 11 days, and it is difficult to pass the brain-blood checkpoint by dealkylation to become a disubstituted body or a substituted body, and the retention time in the brain is slightly longer. Tributyltin and triphenyltin are highly toxic to insects, bacteria, algae, and the like. Trimethyltin and triethyltin are highly toxic to mammals. The increase in carbon content reduces its toxicity, so tributyltin and triphenyltin are commonly used in pesticides and fishing gear antifouling agents, increasing the amount of release into the environment.