my country’s spermine preparation technology is gradually maturing, and the scale of production capacity is gradually shrinking

Spermine, also known as spermine, is a polyamine substance produced in the body from S-adenosylmethionine and putrescine (butanediamine) catalyzed by various enzymes. It can be used to promote cell proliferation. The chemical formula of spermine is C10H26N4. It mostly appears as a white or off-white powder crystal under normal temperature and pressure. Under acidic conditions, spermine can combine with DNA in viruses and bacteria to improve the stability and flexibility of DNA molecules. get a big improvement.

At this stage, my country’s spermine preparation technology is gradually mature, which can be roughly divided into chemical synthesis method, biosynthesis method, liquid phase method, gas phase method, etc. Among them, the chemical synthesis method has become the mainstream production process in the industry due to its advantages such as low production cost, high production efficiency, and stable product quality.

At present, my country’s spermine industry chain has basically been formed. The upstream of the industrial chain is mainly the raw material industry, providing raw materials such as sodium hydroxide, potassium hydroxide, and urea; the midstream is mainly the spermine production industry, responsible for the production and manufacturing of spermine; the downstream is mainly the application field, mostly used in pesticides and cosmetics , textile, chemical industry, plastics and other fields. Among them, the pesticide field has become the largest application field of spermine.

In the field of pesticides, spermine is mostly used in the production of acephate. Acephate, as a systemic insecticide, can effectively remove insect pests, but it can cause serious harm to the human body if used and stored improperly. Therefore, under the guidance of national policies, the application scope of acephate has been reduced, and the market has been severely hit. As the main raw material for the production of acephate, spermine’s market demand has been severely affected.

In addition to the field of pesticides, spermine is also widely used in the field of cosmetics. Spermine, as a typical anionic surfactant, has excellent emulsification, penetration, and decontamination capabilities, and is mostly used in the production of facial cleansers, shower gels and other products.

According to the “China Spermine Industry Market In-depth Research and Development Prospects Forecast Report 2023-2028” released by the Industrial Research Center, but Affected by the severe shrinkage of the acephate market, the overall demand for spermine has declined sharply. Against this background, some spermine companies in my country have gradually withdrawn from the market and their production capacity has gradually shrunk. In 2022, my country’s total spermine production capacity will be less than 80,000 tons.

At present, my country’s large-scale spermine production companies mainly include Jingzhou Sancaitang Chemical Technology Co., Ltd., Hubei Chishun Chemical Co., Ltd., ADAMA Co., Ltd., Hubei Sanonda Group, etc. Among them, Hubei Sanonda Group has the largest production capacity and is the largest spermine manufacturer.

Industry analysts said that in recent years, the production technology of spermine enterprises in my country has continued to improve, and the performance of spermine products has improved, and its application The field gradually widened. In addition to the cosmetics and pharmaceutical fields, spermine companies are also actively exploring other fields, such as the feed field. New feed additives may become a new development driver for the spermine industry in the future.