Trifluoroacetic acid (TFA) is an important raw material for organic synthesis. my country’s industry concentration needs to be improved.

Trifluoroacetic acid (TFA), also known as perfluoroacetic acid, has a chemical formula of C2HF3O2 and is an organic compound. Trifluoroacetic acid appears as a colorless, volatile, smoky, transparent liquid with an odor similar to acetic acid. It is soluble in ether, ethanol, acetone, benzene and water. Trifluoroacetic acid is a strong organic acid with characteristics such as irritation, corrosiveness, and low boiling point. It is widely used in many fields such as pesticides, organic synthesis, dyes, and medicine.

There are many synthesis methods for trifluoroacetic acid, including Simons electrolytic fluorination method, 2,3-dichlorohexafluoro-2-butene oxidation method, octafluorobutene-2 ​​oxidation method, etc. The Simons electrolytic fluorination method is a commonly used method in the industrial production of trifluoroacetic acid. This method has the advantages of high yield and good quality of finished products. In recent years, well-known chemical companies around the world have improved the Simons electrolytic fluorination method, including the American 3M Company, the American Phillips Petroleum Company, etc., which has further improved the output and quality of trifluoroacetic acid.

Trifluoroacetic acid is an important raw material for organic synthesis, and trifluoroethanol, trifluoroacetic anhydride, trifluoroacetaldehyde, etc. are its end products. Trifluoroethanol has the characteristics of good chemical stability and weak nucleophilicity. It can be used as acylating agent, fluorination reaction solvent and rubber modifier, and has a wide range of applications. Trifluoroacetic anhydride is also called trifluoroacetic anhydride. It has relatively active chemical properties and excellent hygroscopicity, and can be used as a dehydration condensation agent, organic synthesis reagent and catalyst; trifluoroacetaldehyde is prone to polymerization and can synthesize trifluoromethyl-containing heterocyclic compounds.

According to the “2023-2028 China Trifluoroacetic Acid (TFA) Industry Market In-depth Research and Development Prospects Forecast Report released by the Industrial Research Center 》 shows that trifluoroacetic acid is widely used in many fields such as pesticides, organic synthesis, dyes, and medicine. In the field of pesticides, trifluoroacetic acid can be used to produce quinoline-based herbicides, pyridine-based herbicides, etc.; in the field of organic synthesis, trifluoroacetic acid can be used as a catalyst to participate in the polymerization of aromatic compounds; in the pharmaceutical field, trifluoroacetic acid can be used as a pharmaceutical Intermediates can be used to produce analgesics, antiarrhythmic drugs, etc. Benefiting from the accelerated development of downstream industries, the trifluoroacetic acid market space has further expanded.

The major global producers of trifluoroacetic acid include 3M Company of the United States, Phillips Petroleum Company of the United States, KaliChemie Company of Germany, Asahi Glass Company of Japan, Solvay Group of Belgium, etc. In terms of the local market, my country’s trifluoroacetic acid market has many participants, mainly small and medium-sized enterprises, with low industry concentration. Representative companies include New Era Chemical, Yinglang Chemical, Zhongtian Chemical, etc.

Industry analysts said that trifluoroacetic acid, as a fluorine-containing fine chemical, is widely used in many fields and has good industry development prospects. In the future, with the accelerated development of my country’s trifluoroethanol, trifluoroacetic anhydride, trifluoroacetaldehyde and other industries, the market demand for trifluoroacetic acid will become increasingly strong. At present, my country’s trifluoroacetic acid industry has a low concentration level. It is expected that companies with high-quality trifluoroacetic acid production capabilities will occupy a larger space in the market in the future.