Clothianidin is expected to replace the first generation of neonicotinoid pesticides, and the number of related product registrations in my country continues to grow.

Clothianidin, also known as (E)-1-(2-chloro-1,3-thiazol-5-ylmethyl)-3-methyl-2-2-nitroguanidine, has a chemical formula of C6H8ClN5O2S and is an organic compound. Clothianidin appears as a crystalline solid powder with no special odor and is soluble in most organic solvents and water. Clothianidin is a second-generation neonicotinoid insecticide with the advantages of high systemic activity, high selectivity, wider insecticidal range, and high safety. It can be used to control rice planthoppers, aphids, whitefly, and tobacco powder. Lice, planthoppers and other sucking pests.

Second-generation neonicotinoid insecticides include clothianidin, thiamethoxam, imidacloprid, etc. Clothianidin is a representative product of the second-generation neonicotinoid insecticides. Compared with the first-generation neonicotinoid insecticides, it has the advantages of high systemic activity and broad insecticidal spectrum, and its market demand continues to grow. According to the “2023-2028 China Clothianidin Industry Market In-depth Research and Development Prospects Forecast Report released by the Industrial Research Center, Global sales of clothianidin will reach nearly US$500 million in 2022, setting a record high. It is expected that in the future, as technology maturity increases, clothianidin is expected to replace the first generation of neonicotinoid pesticides and become the mainstream of the neonicotinoid pesticide market.

There are many methods for preparing clothianidin, but all of them have defects to varying degrees, resulting in a low yield rate in my country. In recent years, Chinese companies have continued to increase research on preparation methods of clothianidin and have made many new progresses. The invention patent “A Preparation Method of Clothianidin” disclosed by Zhongqi Co., Ltd. proposes a method for preparing clothianidin using a tetraalkyl ammonium hydroxide catalyst. This method has the characteristics of simple operation, easy purification, low production cost, and low raw materials. Easy to get and other advantages.

Clothianidin can be used to control various sucking pests such as rice planthoppers, aphids, whiteflies, whiteflies tabaci, and planthoppers, and is widely used in crop planting scenarios. In recent years, with in-depth research, the application scope of clothianidin has been further expanded, and the field of seed treatment is its emerging demand. As the development of downstream industries accelerates, the number of registered products containing clothianidin in my country continues to grow, reaching nearly 300 in 2022.

The major global manufacturers of clothianidin include Sumitomo Chemical of Japan, Bayer CropScience of Germany, FMC of the United States, etc. In terms of the local market, attracted by market prospects, the number of companies in my country’s clothianidin industry continues to grow. Yuheng Chemical, Weiyuan Biochemical, Zhongqi Co., Ltd., and Hailier Chemical Co., Ltd. are the main manufacturers of clothianidin in my country. Among them, Zhongqi Co., Ltd. has an annual production capacity of 1,000 tons, ranking first in my country.

Industry analysts said that clothianidin, as a second-generation neonicotinoid insecticide, can be used to control a variety of pests. It can also be used as a seed treatment agent, and the industry has broad prospects for development. In recent years, with the growth of market demand and the improvement of independent research and development capabilities of local enterprises, the maturity of my country’s clothianidin technology has further improved, driving the development of the clothianidin industry to accelerate.