Dithiothreitol (DTT) market demand is growing, but industry development still faces challenges

Dithiothreitol (DTT), also known as dithiothreitol and Cleland’s reagent, has a chemical formula of C4H10O2S2 and is a small molecule organic reducing agent. Dithiothreitol appears as white needles or white solid particles and is easily soluble in water, ethyl acetate, ethanol, ether and acetone.

According to the “2023-2028 China Dithiothreitol (DTT) Industry Market In-depth Research and Development Prospects Forecast Report span>》shows that dithiothreitol has excellent solubility and reducing properties and is widely used in biomedicine, biotechnology and other fields. In the field of biomedicine, dithiothreitol can be used as a protein sulfhydryl protectant, cell tissue detoxifier, radiation protection agent, etc., for the preparation of vaccine preparations, nucleic acid detection reagents, etc.; in the field of biotechnology, dithiothreitol can be used as Protein lysis reagent for DNA extraction, etc. In recent years, with the rapid development of my country’s biomedicine and biotechnology industries, the market demand for dithiothreitol has continued to grow.

Dithiothreitol has excellent performance and has played an important role in many scientific research achievements in my country. In June 2023, the team of Zheng Meiling, a researcher at the Institute of Physics and Chemistry Technology of the Chinese Academy of Sciences, successfully made vinyl ester transparent using femtosecond laser two-photon polymerization technology using dithiothreitol as a chemical cross-linking agent and P2CK as a two-photon initiator. The structural resolution of acid hydrogels has been further improved, and this research will be widely used in the biomedical field in the future.

The major global manufacturers of dithiothreitol include Canada’s BioVectra and India’s Siddhi Vinayaka Spechem. my country’s dithiothreitol industry is highly concentrated, with leading companies occupying a dominant position in the market. The main production companies include Shanghai Aladdin Biochemical Technology Co., Ltd., Zhangjiajie Hengkang Biopharmaceutical Co., Ltd., Suzhou Haofan Biological Co., Ltd., etc. Haofan Biotech focuses on the research and development, production and sales of peptide synthesis reagents and drugs. The quality of its dithiothreitol has a competitive advantage in the global market.

The dithiothreitol market has broad prospects, but industry development still faces many challenges. On the one hand, the traditional preparation methods of dithiothreitol include threitol method, 1,3-butadiene method, etc. The above methods have problems such as low yield of finished products and easy to cause environmental pollution, while emerging green synthesis methods have not yet been realized. Industrial production; on the other hand, dithiothreitol has poor chemical stability. TCEP hydrochloride has the advantages of wide compatibility, wide pH working range and good chemical stability, and will become an upgraded substitute for dithiothreitol in the future. .

Industry analysts said that dithiothreitol, as a commonly used small molecule organic reducing agent, has great application prospects in the fields of biomedicine and biotechnology. better. In the future, as my country’s scientific research level continues to improve, the market demand for dithiothreitol will further grow. However, at present, the development of my country’s dithiothreitol industry still faces many challenges. Local companies urgently need to increase investment in research and development to improve product quality and technological maturity.