Mannitol is in strong demand in the pharmaceutical field and the industry has good development prospects

Mannitol, also known as mannitol, is an isomer of sorbitol. Its chemical formula is C6H14O6 and it is an organic compound. Mannitol appears as a white crystalline powder with the sweet taste of sucrose, is easily soluble in dilute acid solution and water, and is slightly soluble in ethanol. Mannitol is mainly used as a pharmaceutical excipient. It has the effects of dilating renal blood vessels, dehydrating tissues, reducing tissue edema, and being a diuretic. It can be used to treat diseases such as renal failure and cerebral edema.

The main production methods of mannitol include microbial fermentation, plant extraction and chemical synthesis. The microbial fermentation method refers to the use of Zygosaccharomyces ruckeri to ferment glucose, sucrose, and fructose in the order to finally produce high-purity mannitol. However, at present, the development of this method is not yet mature; the plant extraction method uses kelp as the main raw material, and after soaking, Mannitol is finally produced through processes such as concentration, iodine scouring, concentration, cooling, and crystallization. This method is a traditional production method for mannitol, but the process is complex and can easily cause environmental pollution; chemical synthesis is the current mainstream production method for mannitol. Large-scale production has been achieved.

In recent years, driven by market demand, my country’s mannitol production has continued to grow. According to statistics from the China Starch Industry Association, my country’s mannitol production will reach 25,000 tons in 2021, an increase of 19.7% over the previous year. Guangdong, Shandong and Jiangsu are the main producing areas of mannitol in my country, and the above three provinces account for nearly 70% of my country’s total output. At present, my country’s mannitol production can fully meet the demand of the local market, and its export scale continues to expand. According to statistics from the General Administration of Customs of China, my country’s mannitol export volume will reach 12,000 tons in 2021, a year-on-year increase of 12.5%.

According to the “2022-2027 China Mannitol Market Feasibility Research Report released by the Industrial Research Center, as a functional Sugar alcohols, mannitol are widely used. Light industry, chemical industry, medicine and food are the main demand sides of mannitol, among which the demand in the pharmaceutical field accounts for 60.0%. In the pharmaceutical field, mannitol can be used to produce mannitol injection, which can reduce intraocular pressure in patients, treat cerebral edema, and can also be used as a surgical irrigation agent. Driven by downstream demand, my country’s mannitol market continues to expand, reaching 2.50 billion yuan in 2021.

The main manufacturers of mannitol in my country include Qingdao Mingyue Seaweed Group Co., Ltd., Shandong Tianli Pharmaceutical Co., Ltd. and Shijiazhuang Huaxu Pharmaceutical Co., Ltd. As the industrial structure layout continues to be optimized, the concentration of my country’s mannitol industry continues to increase. Tianli Pharmaceutical, as the largest sugar alcohol manufacturer in Asia, occupies a large share of my country’s mannitol market. Industry analysts said that mannitol has excellent performance and strong demand in the pharmaceutical field. With the rapid development of downstream industries, its market size will further expand expand. Driven by the technological innovation of leading enterprises, my country’s mannitol production and quality will be greatly improved.