Chloropromazine Hydrochlorode Chloropromazine Hydrochlorode

Structural formula

• Numbering system
• Physical property data
• Toxicological data
• Ecological data
• Molecular structure data
• Computing chemical data
• More
  • Properties and Stability
  • Storage method
  • Synthesis method
  • Purpose

Numbering system

CAS number:69-09-0

MDL number:MFCD00012654

EINECS number:200-701-3

RTECS number:200-701-3

BRN number:3779989

PubChem number:24277891

Physical property data

1. Character:White or milky white crystalline powder, hygroscopic, slightly odorous, extremely bitter in taste, easily oxidized in air or Gradates to reddish brown in sunlight

2. Density (g/mL,25/4℃): Unsure

3. Relative vapor density (g/mL,AIR=1): Unsure

4. Melting point (ºC):179-180℃（ 194-196℃ ).

5. Boiling point (ºC,Normal pressure): Uncertain

6. Boiling point (ºC, 5.2kPa): Unsure

7. Refractive index:Not sure

8. Flash point (ºC): Unsure

9. Specific optical rotation (º): Unsure

10. Autoignition point or ignition temperature (ºC): No�Quantity: 0

11. Determine the number of atomic stereocenters: 0

12. Uncertain number of atomic stereocenters: 0

13. Determine chemical bonds Number of stereocenters: 0

14. Number of stereocenters of uncertain chemical bonds: 0

15. Number of covalent bond units: 2

Properties and stability

None

Storage method

Keep it sealed and protected from light.

Synthesis method

By2-Chlorophenothiazine[92-39-7]Condensation and salt formation. 1.Condensation in reaction Add 2- Chlorophenothiazine and toluene, then add sodium hydroxide, stir and heat to reflux, remove moisture, and in 110℃ dripping1-Chlorine-3-Toluene solution of dimethylaminopropane, the reactant is decompressed to recover toluene to obtain chlorpromazine,C17H19CIN2S,[50-53-3]. 2.Salt Stir and heat chlorpromazine and isopropyl alcohol until 40℃, access dry hydrogen chloride to pH 4-5, to obtain chlorpromazine hydrochloride as a salt.

Purpose

has central stabilizing, antiemetic, anticonvulsant, anti- Adrenaline and other effects. Used to treat schizophrenia and mania. Anxiety disorders, mental disorders, nausea, vomiting, etc. It can also be used for artificial hibernation and low-temperature anesthesia.

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Purpose

has central stabilizing, antiemetic, anticonvulsant, anti- Adrenaline and other effects. Used to treat schizophrenia and mania. Anxiety disorders, mental disorders, nausea, vomiting, etc. It can also be used for artificial hibernation and low-temperature anesthesia.