Chlordiazepoxide Chlordiazepoxide

Structural formula

• Numbering system
• Physical property data
• Toxicological data
• Ecological data
• Molecular structure data
• Computing chemical data
• More
  • Properties and Stability
  • Storage method
  • Synthesis method
  • Purpose

Numbering system

CAS number:58-25-3

MDL number:None

EINECS number:200-371-0

RTECS number:None

BRN number:None

PubChem ID:None

Physical property data

1. Character: light yellow crystalline powder. It has a slight odor and an extremely bitter taste.

2. Density ( g/mL,25/4℃) ： Undetermined

3.   Relative vapor density (g/mL,AIR=1): Undetermined

4. Melting point ( ºC): 236- 236.5

5. Boiling point ( ºC,Normal pressure): Undetermined

6. Boiling point ( ºC,5.2kPa): Undetermined

7. Refractive Index: Undetermined

8. Flashpoint (ºC): Undetermined

9. Specific optical rotation (º): [α]D24 +109°（C=4, in ethanol )

10. Autoignition point or ignition temperature (ºC): Not OK

11. Vapor pressure (kPa,25ºC): Undetermined

12. Saturation vapor pressure (kPa,60ºC): Undetermined 4. Surface Tension (dyne/cm):48.4

5. Polarizability(10^-24cm³): 33.28

Compute chemical data

1. Reference value for hydrophobic parameter calculation (XlogP): None

2. Number of hydrogen bond donors: 1

3. Number of hydrogen bond acceptors: 3

4. Number of rotatable chemical bonds: 1

5. Number of tautomers: none

6. Topological molecule polar surface area 48.2

7. Number of heavy atoms: 21

8. Surface charge: 0

9. Complexity: 580

10. Number of isotope atoms: 0

11. Determine the number of atomic stereocenters: 0

12. Uncertain number of atomic stereocenters: 0

13. Determine the number of chemical bond stereocenters: 0

14. Number of uncertain chemical bond stereocenters: 0

15. Number of covalent bond units: 1

Properties and stability

None

Storage method

This product should be sealed and stored in a cool, dry place away from light.

Synthesis method

Will2-Amino-5-Chlorine–Diphenyl Reflux reaction of ketone and hydroxylamine hydrochloride in ethanol10hours, get2-Amino -5-Chlorine–benzophenone oxime, and then cyclization and expansion Obtained by ring. The crude product is recrystallized with ethanol and decolorized with activated carbon to obtain the finished product.

Purpose

This product is a weak tranquilizer with sedative, anti-anxiety, anti-convulsant and muscle relaxant effects. Mainly used to treat anxiety, obsessive-compulsive neurosis, neurasthenia, insomnia and hypertension. Combined with other anti-epileptic drugs, it can suppress major or minor epileptic seizures. Taking large amounts over a long period of time can lead to addiction.

t; FONT-FAMILY: Arial; mso-fareast-font-family: 宋体; mso-font-kerning: 1.0pt; mso-ansi-language: EN-US; mso-fareast-language: ZH-CN; mso-bidi -language: AR-SA”>10 hours, get2-Amino– 5-Chlorine–Benbenzophenone oxime is obtained by cyclization and ring expansion. The crude product is recrystallized with ethanol and decolorized with activated carbon to obtain the finished product.

Purpose

This product is a weak tranquilizer with sedative, anti-anxiety, anti-convulsant and muscle relaxant effects. Mainly used to treat anxiety, obsessive-compulsive neurosis, neurasthenia, insomnia and hypertension. Combined with other anti-epileptic drugs, it can suppress major or minor epileptic seizures. Taking large amounts over a long period of time can lead to addiction.