Puromycin Dihydrochloride Puromycin Dihydrochloride

Structural formula

Business number	019L
Molecular formula	C22H29N7O5·2HCl
Molecular weight	544.43
label	Puromycin dihydrochloride hydrate

• Numbering system
• Physical property data
• Toxicological data
• Ecological data
• Molecular structure data
• Computing chemical data
• More
  • Properties and Stability
  • Storage method
  • Synthesis method
  • Purpose

Numbering system

CAS number:58-58-2

MDL number:MFCD00067313

EINECS number:200-387-8

RTECS number:AU7355000

BRN number:None

PubChem ID:None

Physical property data

1. Characteristics: Crystalline. Hygroscopic. Sensitive to light.

2. Density ( g/mL,25/4℃) ： Undetermined

3. relative Vapor density (g/mL,Air=1 ): Undetermined

4. Melting point ( ºC): 175.5~177.0

5. Boiling point ( ºC,Normal pressure): Undetermined

6. Boiling point ( ºC): 140-150℃（1.33×10-5kPa）

7. Refractive Index: Undetermined

8. Flashpoint (ºC): Undetermined

9. Specific optical rotation (º): -11

10. Autoignition point or ignition temperature (ºC): Not OK

11. Vapor pressure (kPa,25ºC): Undetermined

12. Saturation vapor pressure (kPa,60ºC): Undetermined

18. Lower explosion limit (%,V/V): Not OK

19. Solubility: Easily soluble in water.

Toxicological data

1, acute toxicity: mice oral LD50: 720mg/kg; mouse abdominal cavity LD50: 580mg/kg; mouse intravenous LD50: .335mg/kg; Guinea pig oral LD50: 600mg/kg;
Guinea pig abdominal cavity LD50: 287mg/kg; guinea pig intramuscular LD50：202mg/kg
2, other multiple dose toxicity: rat Abdominal TDLo: 1mg/kg/10D-I; Dog intramuscular TDLo >：150mg/kg/3D-I
3 , mutagenicity: DNA inhibition test: mouse abdominal cavity: 333mg/kg; mutation Test system – and not otherwise specified: Mouse abdominal cavity: 333mg/kg;
Cytogenetic analysis: Mouse peritoneal cavity: 100mg/kg

Ecological data

None

Molecular structure data

5. Molecular property data:

1. Molar refractive index: 120.56

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Compute chemical data

None

Properties and stability

None

Storage method

This product should be sealed with argon gas0 Store in a dry place below ℃ and away from light.

Synthesis method

By Streptococcus albicans (Streptomyces.alboniger) fermentation.

Purpose

Biochemical research. Protein synthesis inhibitor. Prevents the growth of bacteria, algae, protists and mammalian cells.

S> Cytogenetic analysis: Mouse peritoneal cavity: 100mg/kg

Ecological data

None

Molecular structure data

5. Molecular property data:

1. Molar refractive index: 120.56

<SPAN lang=EN-US styl

Compute chemical data

None

Properties and stability

None

Storage method

This product should be sealed with argon gas0 Store in a dry place below ℃ and away from light.

Synthesis method

By Streptococcus albicans (Streptomyces.alboniger) fermentation.

Purpose

Biochemical research. Protein synthesis inhibitor. Prevents the growth of bacteria, algae, protists and mammalian cells.